In 1947, Lin Xiaohai founded Haiqiang School of Medical and Technical Studies.

In 1948, Tse-ven Soong founded Private Hainan University Medicine College.

In 1951, Haiqiang School of Medical and Technical Studies and Private Hainan University Medicine College merged as Hainan Medical Specialized School.

In 1952, school was changed to Hainan Medical College.

In 1973, the affiliated hospital was set up.

In 1977, Hainan Medical College started its medical undergraduate program.

In 1983, Hainan Medical College merged into Hainan university.

In 1993, Hainan Medical University established with the approval of State Education Commission.

In 1994, Hainan Medical University was entitled to grant bachelor’s degree.

In 1996, Hainan Medical University passed the undergraduate teaching evaluation of higher education institutions.

In 2000, the main campus was successfully moved to Chengxi.

In 2003, Hainan Medical University was approved to jointly foster postgraduates.

In 2006, Hainan Medical University started international education.

In 2007, the bid for a medical university was launched.

In 2013, Hainan Medical University was authorized to offer master's degree program. In 2014, Hainan Medical University was authorized to offer professional master's degree program.

In 2016, Hainan Nongken General Hospital merged into Hainan Medical University and changed to the second affiliated hospital.

In 2018, Hainan General Hospital merged into Hainan Medical University and named Hainan affiliated Hospital

In 2019, Hainan Medical University was authorized to offer doctoral degree program, and 2 key laboratories of the Ministry of Education were approved.

In 2020, Haikou Municipal People’s Government transferred land of 524693.33 square meter for Guilinyang campus.

In 2021, changing name to medical university was included in higher education institutions plan of the 15th Five-Year Plan of Hainan.

In July 2022, approved by both parties, UWE college of Hainan Medical University established.